Cholsoon Jang

First name

Cholsoon

Last name

Jang

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Flam E, Jang C, Murashige D, Yang Y, Morley M, Jung S, Kantner D, Pepper H, Bedi K, Brandimarto J, Prosser B, Cappola T, Snyder N, Rabinowitz J, Margulies K, Arany Z. Integrated landscape of cardiac metabolism in end-stage human nonischemic dilated cardiomyopathy. Nat Cardiovasc Res. 2022;1(9):817–829. PMCID: PMC9910091

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Murashige D, Jung J, Neinast M, Levin M, Chu Q, Lambert J, Garbincius J, Kim B, Hoshino A, Marti-Pamies I, McDaid K, Shewale S, Flam E, Yang S, Roberts E, Li L, Morley M, Bedi K, Hyman M, Frankel D, Margulies K, Assoian R, Elrod J, Jang C, Rabinowitz J, Arany Z. Extra-cardiac BCAA catabolism lowers blood pressure and protects from heart failure. Cell Metab. 2022;34(11):1749–1764.e7. PMCID: PMC9633425

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Jang C, Hui S, Zeng X, Cowan A, Wang L, Chen L, Morscher R, Reyes J, Frezza C, Hwang H, Imai A, Saito Y, Okamoto K, Vaspoli C, Kasprenski L, Zsido G, Gorman J, Gorman R, Rabinowitz J. Metabolite Exchange between Mammalian Organs Quantified in Pigs. Cell Metab. 2022;34(9):1410. PMCID: PMC9514224

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Zeng X, Xing X, Gupta M, Keber F, Lopez J, Lee Y-C, Roichman A, Wang L, Neinast M, Donia M, Wühr M, Jang C, Rabinowitz J. Gut bacterial nutrient preferences quantified in vivo. Cell. 2022;185(18):3441–3456.e19. PMCID: PMC9450212

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Li X, Hui S, Mirek E, Jonsson W, Anthony T, Lee W, Zeng X, Jang C, Rabinowitz J. Circulating metabolite homeostasis achieved through mass action. Nat Metab. 2022;4(1):141–152. PMCID: PMC9244777

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Yu D, Richardson N, Green C, Spicer A, Murphy M, Flores V, Jang C, Kasza I, Nikodemova M, Wakai M, Tomasiewicz J, Yang S, Miller B, Pak H, Brinkman J, Rojas J, Quinn W, Cheng E, Konon E, Haider L, Finke M, Sonsalla M, Alexander C, Rabinowitz J, Baur J, Malecki K, Lamming D. The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine. Cell Metab. 2021;33(5):905–922.e6. PMCID: PMC8102360

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Cho S, Lee G, Pickering B, Jang C, Park J, He L, Mathur L, Kim S-S, Jung S, Tang H-W, Monette S, Rabinowitz J, Perrimon N, Jaffrey S, Blenis J. mTORC1 promotes cell growth via mA-dependent mRNA degradation. Mol Cell. 2021;81(10):2064–2075.e8. PMCID: PMC8356906

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Murashige D, Jang C, Neinast M, Edwards J, Cowan A, Hyman M, Rabinowitz J, Frankel D, Arany Z. Comprehensive quantification of fuel use by the failing and nonfailing human heart. Science. 2020;370(6514):364–368. PMCID: PMC7871704

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Hui S, Cowan A, Zeng X, Yang L, TeSlaa T, Li X, Bartman C, Zhang Z, Jang C, Wang L, Lu W, Rojas J, Baur J, Rabinowitz J. Quantitative Fluxomics of Circulating Metabolites. Cell Metab. 2020;32(4):676–688.e4. PMCID: PMC7544659

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Jang C, Wada S, Yang S, Gosis B, Zeng X, Zhang Z, Shen Y, Lee G, Arany Z, Rabinowitz J. The small intestine shields the liver from fructose-induced steatosis. Nat Metab. 2020;2(7):586–593. PMCID: PMC8020332

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Guan D, Xiong Y, Trinh T, Xiao Y, Hu W, Jiang C, Dierickx P, Jang C, Rabinowitz J, Lazar M. The hepatocyte clock and feeding control chronophysiology of multiple liver cell types. Science. 2020;369(6509):1388–1394. PMCID: PMC7849028

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Zhao S, Jang C, Liu J, Uehara K, Gilbert M, Izzo L, Zeng X, Trefely S, Fernandez S, Carrer A, Miller K, Schug Z, Snyder N, Gade T, Titchenell P, Rabinowitz J, Wellen K. Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate. Nature. 2020;579(7800):586–591. PMCID: PMC7416516

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Yang L, Canaveras J, Chen Z, Wang L, Liang L, Jang C, Mayr J, Zhang Z, Ghergurovich J, Zhan L, Joshi S, Hu Z, McReynolds M, Su X, White E, Morscher R, Rabinowitz J. Serine Catabolism Feeds NADH when Respiration Is Impaired. Cell Metab. 2020;31(4):809–821.e6. PMCID: PMC7397714

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Lanaspa M, Andres-Hernando A, Orlicky D, Cicerchi C, Jang C, Li N, Milagres T, Kuwabara M, Wempe M, Rabinowitz J, Johnson R, Tolan D. Ketohexokinase C blockade ameliorates fructose-induced metabolic dysfunction in fructose-sensitive mice. J Clin Invest. 2018;128(6):2226–2238. PMCID: PMC5983342

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Jang C, Hui S, Zeng X, Cowan A, Wang L, Chen L, Morscher R, Reyes J, Frezza C, Hwang H, Imai A, Saito Y, Okamoto K, Vaspoli C, Kasprenski L, Zsido G, Gorman J, Gorman R, Rabinowitz J. Metabolite Exchange between Mammalian Organs Quantified in Pigs. Cell Metab. 2019;30(3):594–606.e3. PMCID: PMC6726553

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Neinast M, Jang C, Hui S, Murashige D, Chu Q, Morscher R, Li X, Zhan L, White E, Anthony T, Rabinowitz J, Arany Z. Quantitative Analysis of the Whole-Body Metabolic Fate of Branched-Chain Amino Acids. Cell Metab. 2019;29(2):417–429.e4. PMCID: PMC6365191

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Guan D, Xiong Y, Borck P, Jang C, Doulias P-T, Papazyan R, Fang B, Jiang C, Zhang Y, Briggs E, Hu W, Steger D, Ischiropoulos H, Rabinowitz J, Lazar M. Diet-Induced Circadian Enhancer Remodeling Synchronizes Opposing Hepatic Lipid Metabolic Processes. Cell. 2018;174(4):831–842.e12. PMCID: PMC6086765

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Jang C, Chen L, Rabinowitz J. Metabolomics and Isotope Tracing. Cell. 2018;173(4):822–837. PMCID: PMC6034115

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Jang C, Hui S, Lu W, Cowan A, Morscher R, Lee G, Liu W, Tesz G, Birnbaum M, Rabinowitz J. The Small Intestine Converts Dietary Fructose into Glucose and Organic Acids. Cell Metab. 2018;27(2):351–361.e3. PMCID: PMC6032988

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Liu L, Rowe G, Yang S, Li J, Damilano F, Chan M, Lu W, Jang C, Wada S, Morley M, Hesse M, Fleischmann B, Rabinowitz J, Das S, Rosenzweig A, Arany Z. PDK4 Inhibits Cardiac Pyruvate Oxidation in Late Pregnancy. Circ Res. 2017;121(12):1370–1378. PMCID: PMC5722682

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Lee G, Zheng Y, Cho S, Jang C, England C, Dempsey J, Yu Y, Liu X, He L, Cavaliere P, Chavez A, Zhang E, Isik M, Couvillon A, Dephoure N, Blackwell K, Yu J, Rabinowitz J, Cantley L, Blenis J. Post-transcriptional Regulation of De Novo Lipogenesis by mTORC1-S6K1-SRPK2 Signaling. Cell. 2017;171(7):1545–1558.e18. PMCID: PMC5920692

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Hui S, Ghergurovich J, Morscher R, Jang C, Teng X, Lu W, Esparza L, Reya T, Guo J, White E, Rabinowitz J. Glucose feeds the TCA cycle via circulating lactate. Nature. 2017;551(7678):115–118. PMCID: PMC5898814

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Jang C, Oh S, Wada S, Rowe G, Liu L, Chan M, Rhee J, Hoshino A, Kim B, Ibrahim A, Baca L, Kim E, Ghosh C, Parikh S, Jiang A, Chu Q, Forman D, Lecker S, Krishnaiah S, Rabinowitz J, Weljie A, Baur J, Kasper D, Arany Z. A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance. Nat Med. 2016;22(4):421–6. PMCID: PMC4949205

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