1.García-Cañaveras J, Lancho O, Ducker G, Ghergurovich J, Xu X, da Silva-Diz V, Minuzzo S, Indraccolo S, Kim H, Herranz D, Rabinowitz J. SHMT inhibition is effective and synergizes with methotrexate in T-cell acute lymphoblastic leukemia. Leukemia. 2021;35(2):377–388. PMCID: PMC7647950 Reference Link
1.Li A, Ducker G, Li Y, Seoane J, Xiao Y, Melemenidis S, Zhou Y, Liu L, Vanharanta S, Graves E, Rankin E, Curtis C, Massagué J, Rabinowitz J, Thompson C, Ye J. Metabolic Profiling Reveals a Dependency of Human Metastatic Breast Cancer on Mitochondrial Serine and One-Carbon Unit Metabolism. Mol Cancer Res. 2020;18(4):599–611. PMCID: PMC7127984 Reference Link
1.Dekhne A, Shah K, Ducker G, Katinas J, Wong-Roushar J, Nayeen M, Doshi A, Ning C, Bao X, Frühauf J, Liu J, Wallace-Povirk A, O’Connor C, Dzinic S, White K, Kushner J, Kim S, Hüttemann M, Polin L, Rabinowitz J, Li J, Hou Z, Dann C, Gangjee A, Matherly L. Novel Pyrrolo[3,2-]pyrimidine Compounds Target Mitochondrial and Cytosolic One-carbon Metabolism with Broad-spectrum Antitumor Efficacy. Mol Cancer Ther. 2019;18(10):1787–1799. PMCID: PMC6774887 Reference Link
1.Rodriguez A, Ducker G, Billingham L, Martinez C, Mainolfi N, Suri V, Friedman A, Manfredi M, Weinberg S, Rabinowitz J, Chandel N. Serine Metabolism Supports Macrophage IL-1β Production. Cell Metab. 2019;29(4):1003–1011.e4. PMCID: PMC6447453 Reference Link
1.Rodan L, Qi W, Ducker G, Demirbas D, Laine R, Yang E, Walker M, Eichler F, Rabinowitz J, Anselm I, Berry G, Undiagnosed Diseases Network (UDN). 5,10-methenyltetrahydrofolate synthetase deficiency causes a neurometabolic disorder associated with microcephaly, epilepsy, and cerebral hypomyelination. Mol Genet Metab. 2018;125(1-2):118–126. PMCID: PMC6557438 Reference Link
1.Morscher R, Ducker G, Li S, Mayer J, Gitai Z, Sperl W, Rabinowitz J. Mitochondrial translation requires folate-dependent tRNA methylation. Nature. 2018;554(7690):128–132. PMCID: PMC6020024 Reference Link
1.Ducker G, Ghergurovich J, Mainolfi N, Suri V, Jeong S, Li S, Friedman A, Manfredi M, Gitai Z, Kim H, Rabinowitz J. Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma. Proc Natl Acad Sci U S A. 2017;114(43):11404–11409. PMCID: PMC5664509 Reference Link
1.Chen L, Ducker G, Lu W, Teng X, Rabinowitz J. An LC-MS chemical derivatization method for the measurement of five different one-carbon states of cellular tetrahydrofolate. Anal Bioanal Chem. 2017;409(25):5955–5964. PMCID: PMC5737010 Reference Link
1.Ducker G, Chen L, Morscher R, Ghergurovich J, Esposito M, Teng X, Kang Y, Rabinowitz J. Reversal of Cytosolic One-Carbon Flux Compensates for Loss of the Mitochondrial Folate Pathway. Cell Metab. 2016;23(6):1140–1153. PMCID: PMC4909566 Reference Link
1.Ducker G, Rabinowitz J. One-Carbon Metabolism in Health and Disease. Cell Metab. 2017;25(1):27–42. PMCID: PMC5353360 Reference Link