The cerebellum, sensitive periods, and autism.

Publication Year
2014

Type

Journal Article
Abstract

Cerebellar research has focused principally on adult motor function. However, the cerebellum also maintains abundant connections with nonmotor brain regions throughout postnatal life. Here we review evidence that the cerebellum may guide the maturation of remote nonmotor neural circuitry and influence cognitive development, with a focus on its relationship with autism. Specific cerebellar zones influence neocortical substrates for social interaction, and we propose that sensitive-period disruption of such internal brain communication can account for autism's key features.

Journal
Neuron
Volume
83
Issue
3
Pages
518-32
Date Published
2014 Aug 06
ISSN Number
1097-4199
Alternate Journal
Neuron
PMCID
PMC4135479
PMID
25102558