| Title | The cerebellum, sensitive periods, and autism. |
| Publication Type | Journal Article |
| Year of Publication | 2014 |
| Authors | Wang, SS-H, Kloth, AD, Badura, A |
| Journal | Neuron |
| Volume | 83 |
| Issue | 3 |
| Pagination | 518-32 |
| Date Published | 2014 Aug 06 |
| ISSN | 1097-4199 |
| Keywords | Autistic Disorder, Brain Mapping, Cerebellum, Cognition, Gene Expression, Humans, Learning, Male |
| Abstract | <p>Cerebellar research has focused principally on adult motor function. However, the cerebellum also maintains abundant connections with nonmotor brain regions throughout postnatal life. Here we review evidence that the cerebellum may guide the maturation of remote nonmotor neural circuitry and influence cognitive development, with a focus on its relationship with autism. Specific cerebellar zones influence neocortical substrates for social interaction, and we propose that sensitive-period disruption of such internal brain communication can account for autism's key features.</p> |
| DOI | 10.1016/j.neuron.2014.07.016 |
| Alternate Journal | Neuron |
| PubMed ID | 25102558 |
| PubMed Central ID | PMC4135479 |
| Grant List | F31 MH098651 / MH / NIMH NIH HHS / United States R01 NS045193 / NS / NINDS NIH HHS / United States T32 GM007388 / GM / NIGMS NIH HHS / United States |
