The cell biology of planar cell polarity. Author Danelle Devenport Publication Year 2014 Type Journal Article Abstract Planar cell polarity (PCP) refers to the coordinated alignment of cell polarity across the tissue plane. Key to the establishment of PCP is asymmetric partitioning of cortical PCP components and intercellular communication to coordinate polarity between neighboring cells. Recent progress has been made toward understanding how protein transport, endocytosis, and intercellular interactions contribute to asymmetric PCP protein localization. Additionally, the functions of gradients and mechanical forces as global cues that bias PCP orientation are beginning to be elucidated. Together, these findings are shedding light on how global cues integrate with local cell interactions to organize cellular polarity at the tissue level. Keywords Animals, Drosophila, Models, Biological, Signal Transduction, Cell Communication, Cues, Cell Polarity, Body Patterning Journal J Cell Biol Volume 207 Issue 2 Pages 171-9 Date Published 2014 Oct 27 ISSN Number 1540-8140 DOI 10.1083/jcb.201408039 Alternate Journal J Cell Biol PMCID PMC4210441 PMID 25349257 PubMedPubMed CentralGoogle ScholarBibTeXEndNote X3 XML