Boron binding with the quorum sensing signal AI-2 and analogues. Author Martin Semmelhack, Shawn Campagna, Charlotte Hwa, Michael Federle, Bonnie Bassler Publication Year 2004 Type Journal Article Abstract [reaction: see text] The unstable bacterial metabolic product, DPD, and the related natural product, laurencione, are shown to have a high affinity for borate complexation, through the hydrated analogue. The boron complex of DPD is Vibrio harveyi AI-2, an interspecies quorum sensing signal in bacteria, and an affinity column with a borate resin is effective in providing the first method for concentrating and purifying V. harveyi AI-2 from the biosynthetic product. Keywords Vibrio, Molecular Structure, Pentanes, Magnetic Resonance Spectroscopy, Boron Journal Org Lett Volume 6 Issue 15 Pages 2635-7 Date Published 2004 Jul 22 ISSN Number 1523-7060 DOI 10.1021/ol048976u Alternate Journal Org Lett PMID 15255709 PubMedGoogle ScholarBibTeXEndNote X3 XML