Title | The Bony Side of Endothelial Cells in Prostate Cancer. |
Publication Type | Journal Article |
Year of Publication | 2017 |
Authors | Peng, J, Kang, Y |
Journal | Dev Cell |
Volume | 41 |
Issue | 5 |
Pagination | 451-452 |
Date Published | 2017 Jun 05 |
ISSN | 1878-1551 |
Keywords | Bone Neoplasms, Cell Line, Tumor, Endothelial Cells, Humans, Male, Osteoblasts, Prostatic Neoplasms |
Abstract | <p>Prostate cancer bone metastases are primarily osteoblastic, but the source of bone-forming cells in these lesions remains poorly defined. In this issue of Developmental Cell, Lin et al. (2017) demonstrate that tumor-associated endothelial cells can give rise to osteoblasts in prostate cancer through endothelial-to-osteoblast (EC-to-OSB) conversion.</p> |
DOI | 10.1016/j.devcel.2017.05.015 |
Alternate Journal | Dev Cell |
PubMed ID | 28586639 |