| Title | Blowing Off Steam: Virus Inhibition of cGAS DNA Sensing. |
| Publication Type | Journal Article |
| Year of Publication | 2015 |
| Authors | Diner, BA, Cristea, IM |
| Journal | Cell Host Microbe |
| Volume | 18 |
| Issue | 3 |
| Pagination | 270-2 |
| Date Published | 2015 Sep 09 |
| ISSN | 1934-6069 |
| Keywords | DNA, Viral, Herpesvirus 8, Human, Host-Pathogen Interactions, Humans, Immune Evasion, Nucleotidyltransferases, Viral Proteins |
| Abstract | <p>Detection of viral DNA is essential for eliciting mammalian innate immunity. However, viruses have acquired effective mechanisms for blocking host defense. Indeed, in this issue of Cell Host & Microbe, Wu et al. (2015) discover a herpesviral strategy for inhibiting the prominent host sensor of viral DNA, cGAS.</p> |
| DOI | 10.1016/j.chom.2015.08.012 |
| Alternate Journal | Cell Host Microbe |
| PubMed ID | 26355212 |
| PubMed Central ID | PMC4920077 |
| Grant List | R01 GM114141 / GM / NIGMS NIH HHS / United States R21 AI102187 / AI / NIAID NIH HHS / United States |
