The biochemistry of memory.

TitleThe biochemistry of memory.
Publication TypeJournal Article
Year of Publication2013
AuthorsStock, JB, Zhang, S
JournalCurr Biol
Date Published2013 Sep 09
KeywordsAnimals, Bacterial Physiological Phenomena, Biochemistry, Humans, Learning, Memory

<p>Almost fifty years ago, Julius Adler initiated a program of research to gain insights into the basic biochemistry of intelligent behavior by studying the molecular mechanisms that underlie the chemotactic responses of Escherichia coli. All living organisms share elements of a common biochemistry for metabolism, growth and heredity - why not intelligence? Neurobiologists have demonstrated that this is the case for nervous systems in animals ranging from worms to man. Motile unicellular organisms such as E. coli exhibit rudimentary behaviors that can be loosely described in terms of cognitive phenomena such as memory and learning. Adler's initiative at least raised the prospect that, because of the numerous experimental advantages provided by E. coli, it would be the first organism whose behavior could be understood at molecular resolution.</p>

Alternate JournalCurr Biol
PubMed ID24028956
PubMed Central IDPMC3971467
Grant ListR01 AT006868 / AT / NCCIH NIH HHS / United States