Title | The Biochemical Evolution of Protein Complexes. |
Publication Type | Journal Article |
Year of Publication | 2016 |
Authors | Greco, TM, Cristea, IM |
Journal | Trends Biochem Sci |
Volume | 41 |
Issue | 1 |
Pagination | 4-6 |
Date Published | 2016 Jan |
ISSN | 0968-0004 |
Keywords | Animals, Evolution, Molecular, Humans, Multiprotein Complexes, Protein Interaction Maps |
Abstract | <p>Over the past decade, it became evident that proteins perform critical functions as components of specialized macromolecular complexes. Here, we discuss a recent study by Wan and colleagues, which highlights the significance of protein complexes by studying their conservation in organisms separated by up to a billion years of evolution.</p> |
DOI | 10.1016/j.tibs.2015.11.007 |
Alternate Journal | Trends Biochem Sci |
PubMed ID | 26682499 |
PubMed Central ID | PMC4706493 |
Grant List | R01 GM114141 / GM / NIGMS NIH HHS / United States R01 HL127640 / HL / NHLBI NIH HHS / United States GM114141 / GM / NIGMS NIH HHS / United States HL127640 / HL / NHLBI NIH HHS / United States |