Bidirectional communication in oogenesis: a dynamic conversation in mice and Drosophila.

TitleBidirectional communication in oogenesis: a dynamic conversation in mice and Drosophila.
Publication TypeJournal Article
Year of Publication2022
AuthorsDoherty, CA, Amargant, F, Shvartsman, SY, Duncan, FE, Gavis, ER
JournalTrends Cell Biol
Volume32
Issue4
Pagination311-323
Date Published2022 04
ISSN1879-3088
KeywordsAnimals, Communication, Drosophila, Humans, Mice, Oocytes, Oogenesis
Abstract

<p>In most animals, the oocyte is the largest cell by volume. The oocyte undergoes a period of large-scale growth during its development, prior to fertilization. At first glance, tissues that support the development of the oocyte in different organisms have diverse cellular characteristics that would seem to prohibit functional comparisons. However, these tissues often act with a common goal of establishing dynamic forms of two-way communication with the oocyte. We propose that this bidirectional communication between oocytes and support cells is a universal phenomenon that can be directly compared across species. Specifically, we highlight fruit fly and mouse oogenesis to demonstrate that similarities and differences in these systems should be used to inform and design future experiments in both models.</p>

DOI10.1016/j.tcb.2021.11.005
Alternate JournalTrends Cell Biol
PubMed ID34922803
PubMed Central IDPMC8917990
Grant ListR21 HD098498 / HD / NICHD NIH HHS / United States
R01 HD093726 / HD / NICHD NIH HHS / United States
T32 GM007388 / GM / NIGMS NIH HHS / United States
R01 HD105752 / HD / NICHD NIH HHS / United States
R01 GM134204 / GM / NIGMS NIH HHS / United States
R35 GM126967 / GM / NIGMS NIH HHS / United States