A.J. te Velthuis
Assistant Professor of Molecular Biology
Contact
aj.te.velthuis@princeton.edu 609-258-2053
Thomas Laboratory, 103
Faculty Assistant
Antoinette JohnsonEducation
- Ph.D. Medicine (Molecular Virology) Leiden University, Leiden, The Netherlands
- B.Sc. Biology Leiden University, Leiden, The Netherlands
Research Area
Microbiology & VirologyResearch Focus
Innate immune responses and replication of RNA virusesWebsite
Innate immune responses and replication of RNA viruses
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. Transient RNA structures cause aberrant influenza virus replication and innate immune activation. Sci Adv. 2022 ;8(36):eabp8655.
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. Decoding the Role of Temperature in RNA Virus Infections. mBio. 2022 ;13(5):e0202122.
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. Tinker, tailor, antiviral: RNA virus inhibition by induced recombination. Trends Biochem Sci. 2022 ;47(6):456-458.
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. The Host Factor ANP32A Is Required for Influenza A Virus vRNA and cRNA Synthesis. J Virol. 2022 ;96(4):e0209221.
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. Enisamium Inhibits SARS-CoV-2 RNA Synthesis. Biomedicines. 2021 ;9(9).
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. Structural insights into RNA polymerases of negative-sense RNA viruses. Nat Rev Microbiol. 2021 ;19(5):303-318.
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. Influenza A Virus Defective Viral Genomes Are Inefficiently Packaged into Virions Relative to Wild-Type Genomic RNAs. mBio. 2021 ;12(6):e0295921.
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. The influenza virus RNA polymerase as an innate immune agonist and antagonist. Cell Mol Life Sci. 2021 ;78(23):7237-7256.
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. Understanding viral replication and transcription using single-molecule techniques. Enzymes. 2021 ;49:83-113.
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. Structure and Function of the Influenza Virus Transcription and Replication Machinery. Cold Spring Harb Perspect Med. 2020 ;10(9).