A.J. te Velthuis Position Assistant Professor of Molecular Biology Website te Velthuis lab website Office Phone 609-258-2053 Email [email protected] Assistant Ellen Brindle-Clark Office Thomas Laboratory, 103 Bio/Description FocusInnate immune responses and replication of RNA virusesResearchInnate immune responses and replication of RNA viruses Education Ph.D. Medicine (Molecular Virology) Leiden University, Leiden, The NetherlandsB.Sc. Biology Leiden University, Leiden, The Netherlands Selected Publications 1.Bisht K, Velthuis A. Decoding the Role of Temperature in RNA Virus Infections. mBio. 2022;13(5):e0202122. PMCID: PMC9600459 1.Pitre E, Velthuis A. Tinker, tailor, antiviral: RNA virus inhibition by induced recombination. Trends Biochem Sci. 2022;47(6):456–458. PMID: 35123872 1.Nilsson-Payant B, tenOever B, Velthuis A. The Host Factor ANP32A Is Required for Influenza A Virus vRNA and cRNA Synthesis. J Virol. 2022;96(4):e0209221. PMCID: PMC8865535 1.Elli S, Bojkova D, Bechtel M, Vial T, Boltz D, Muzzio M, Peng X, Sala F, Cosentino C, Goy A, Guerrini M, Müller L, Cinatl J, Margitich V, Velthuis A. Enisamium Inhibits SARS-CoV-2 RNA Synthesis. Biomedicines. 2021;9(9). PMCID: PMC8467925 1.Velthuis A, Grimes J, Fodor E. Structural insights into RNA polymerases of negative-sense RNA viruses. Nat Rev Microbiol. 2021;19(5):303–318. PMCID: PMC7832423 1.Alnaji F, Reiser W, Rivera-Cardona J, Velthuis A, Brooke C. Influenza A Virus Defective Viral Genomes Are Inefficiently Packaged into Virions Relative to Wild-Type Genomic RNAs. mBio. 2021;12(6):e0295921. PMCID: PMC8609359 1.Pitre E, Velthuis A. Understanding viral replication and transcription using single-molecule techniques. Enzymes. 2021;49:83–113. PMID: 34696840 1.Fodor E, Velthuis A. Structure and Function of the Influenza Virus Transcription and Replication Machinery. Cold Spring Harb Perspect Med. 2020;10(9). PMCID: PMC7334866 Related News Could antiviral fabrics go viral? Research Area Microbiology, Virology & Immunology