
A.J. te Velthuis
Position
Assistant Professor of Molecular Biology
Website
Office Phone
Email
Assistant
Office
Thomas Laboratory, 103
Bio/Description
Focus
Innate immune responses and replication of RNA virusesResearch
Innate immune responses and replication of RNA viruses
Education
- Ph.D. Medicine (Molecular Virology) Leiden University, Leiden, The Netherlands
- B.Sc. Biology Leiden University, Leiden, The Netherlands
Selected Publications
- 1.Bisht K, Velthuis A. Decoding the Role of Temperature in RNA Virus Infections. mBio. 2022;13(5):e0202122. PMCID: PMC9600459
- 1.Pitre E, Velthuis A. Tinker, tailor, antiviral: RNA virus inhibition by induced recombination. Trends Biochem Sci. 2022;47(6):456–458. PMID: 35123872
- 1.Nilsson-Payant B, tenOever B, Velthuis A. The Host Factor ANP32A Is Required for Influenza A Virus vRNA and cRNA Synthesis. J Virol. 2022;96(4):e0209221. PMCID: PMC8865535
- 1.Elli S, Bojkova D, Bechtel M, Vial T, Boltz D, Muzzio M, Peng X, Sala F, Cosentino C, Goy A, Guerrini M, Müller L, Cinatl J, Margitich V, Velthuis A. Enisamium Inhibits SARS-CoV-2 RNA Synthesis. Biomedicines. 2021;9(9). PMCID: PMC8467925
- 1.Velthuis A, Grimes J, Fodor E. Structural insights into RNA polymerases of negative-sense RNA viruses. Nat Rev Microbiol. 2021;19(5):303–318. PMCID: PMC7832423
- 1.Alnaji F, Reiser W, Rivera-Cardona J, Velthuis A, Brooke C. Influenza A Virus Defective Viral Genomes Are Inefficiently Packaged into Virions Relative to Wild-Type Genomic RNAs. mBio. 2021;12(6):e0295921. PMCID: PMC8609359
- 1.Pitre E, Velthuis A. Understanding viral replication and transcription using single-molecule techniques. Enzymes. 2021;49:83–113. PMID: 34696840
- 1.Fodor E, Velthuis A. Structure and Function of the Influenza Virus Transcription and Replication Machinery. Cold Spring Harb Perspect Med. 2020;10(9). PMCID: PMC7334866
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Research Area