Prisca Liberali PhD (FMI Basel) - Webinar

Prisca Liberali PhD (FMI Basel) - Webinar

Butler Seminar Series

Event Date/Location

November 3, 2021 - 12:00 pm to 1:00 pm

Speaker

  • Prisca Liberali sitting at lab bench

    Prisca Liberali

    Senior Group Leader
    FMI in Basel

    Prisca Liberali is a senior group leader at the Friedrich Miescher Institute for Biomedical Research (FMI) in Basel.  She has been trained as a physical organic chemist and then changed fields for her PhD and became a cell biologist.  Prisca Liberali made important contributions in fields ranging from fundamental chemistry to in vivo tissue regeneration.

    Her laboratory works role of self-organization in collective cell behaviors, and how these are coordinated by biochemical and mechanical cues. Because these emergent phenomena have multiple layers of biological organization at different scales, the laboratory develops novel experimental, quantitative and statistical methods required to decoding the design principles of tissue organization.  She received the ERC Starting Grant, became an EMBO YIP and was awarded the Friedrich Miescher price in 2021.

Topic

Design principles of tissue organization during organoid development

Multicellular organisms are composed of cells with identical genomes but different properties and functions. They all develop from one cell to form multicellular structures of astounding complexity. I will present how cellular interactions generate emergent tissue scale properties and drive spatio-temporal coordination during development and regeneration. Moreover, I will present the molecular mechanisms underlying intestinal organoid self-organization and the role of cell-to-cell variability in populations of differentiating cells during symmetry breaking.

Audience

Restricted to faculty, staff and students at Princeton University

Host

Eszter Posfai, Department of Molecular Biology