Gia Voeltz (Colorado Univ-Boulder) Webinar

ER contact sites regulate the biogenesis of other organelles
Date
Nov 11, 2020, 12:00 pm1:00 pm
Location
Thomas Laboratory
Audience
Free and open to the university community and the public.

Speakers

Gia Voeltz
Professor
Colorado Univ-Boulder

Details

Event Description

The past several years have revealed that ER membrane contact sites (MCS) play a major role in regulating the biogenesis and dynamics of other cytoplasmic organelles.  We have made the surprising discovery that MCS formed between dynamic ER tubules and multiple organelles including mitochondria, early and late endosomes, and even RNP granules define the position where these organelles undergo division. Our current goals are to identify the machinery and mechanism behind this ER-associated organelle division process. How can an ER tubule at a MCS trigger the division of another organelle and how is this process regulated in time? How can ER MCS regulate the division of so many different types of organelles? What is common and what is unique at the ER MCS that regulate organelle division. Here we will discuss our new data aimed at unraveling the molecular contributions of factors that localize to ER MCS and provide insight into their mechanistic roles. 

Sponsor
Ileana Cristea & Danelle Devenport, Department of Molecular Biology
Event Category
Butler Seminar Series