David Bartel (Whitehead Institute)

MicroRNAs, poly(A) tails, and a developmental switch in the nature of translational control
Date
Dec 9, 2015, 12:00 pm12:00 pm
Location
Thomas Laboratory, 003
Audience
Free and open to the university community and the public

Speakers

David Bartel, Ph.D.
Principal Investigator Whitehead Institute for Medical Research
HHMI Investigator
Professor of Biology, MIT
Whitehead Institute for Medical Research

Details

Event Description

We have been using molecular and computational approaches to find regulatory RNAs, identify the messages that they regulate, and then investigate molecular consequences of these regulatory interactions as well as their functions during development, oncogenesis, and other biological processes.  This talk will describe our current understanding of microRNAs, the mechanisms by which they repress gene expression, a switch in the nature of translational control that occurs in early metazoan development, and how this switch influences the ultimate consequences of miRNA-mediated repression.  

Sponsor
Alexei Korennykh, Department of Molecular Biology
Event Category
Butler Seminar Series