Christine Mayr, MD PhD (Memorial Sloan Kettering Cancer Center) - Webinar

Protein complex assembly in cytoplasmic condensates
Date
Oct 27, 2021, 12:00 pm1:00 pm
Location
Thomas Laboratory, LTL003
Audience
Restricted to faculty, staff and students at Princeton University

Speakers

Christine Mayr
Rachel Carson Professor of Ecology and Evolutionary Biology
Yale

Details

Event Description

My lab is interested in the functions of 3′UTRs. I will present our new insights into the regulation of mRNA localization to three cytoplasmic compartments and how localized protein synthesis modulates protein output by ten-fold.   

We are also interested in the functions of cytoplasmic condensates in cells. So far, we have discovered TIS granules and the FXR1 network. Both cytoplasmic condensates promote protein complex assembly which requires cooperative action between motifs in mRNAs and motifs in proteins. I will present our unpublished data on FXR1.

 

Sponsor
Liz Gavis, Molecular Biology Dept.
Event Category
Butler Seminar Series