My research uses functional genomics, microscopy, and cell biological approaches to understand the functions of mammalian primary cilia. We further aim to elucidate how ciliary functions are connected to other cellular processes and structures, including the cell cycle that governs cilium formation and the centrosome on which the cilium is built. Lastly, we seek to identify how ciliary defects contribute to disease, with the hope that such information can improve understanding and treatment of associated pathologies. An area of emphasis is the development and application of new functional genomic tools that enable systematic study of ciliary biology.