Date Nov 25, 2024, 12:00 pm – 1:00 pm Location Thomas Laboratory 003 Audience Free and open to the university community and the public. Speakers Shruti Naik, PhD Associate Professor Icahn School of Medicine at Mount Sinai Details Event Description AbstractEpithelial tissues, which line our bodies, are constantly exposed to stressors such as injuries, infections, and harmful stimuli. The resulting deviations from homeostasis are quickly detected by immune cells stationed at these barriers. I discuss intricate communication between the immune system and epithelia that have come to fore through mechanistic studies of tissue repair. When unchecked, this crosstalk can lead to chronic inflammatory disease and fuel pathology through by activating continuous damage-repair cycles. Eavesdropping on the conversation between immunity and the epithelia may thus provide unique means of boosting epithelial barrier function by modulating immune signaling or modulating repair mechanisms to treat inflammatory disease. Sponsor Department of Molecular Biology Contact Ai Ing Lim, Department of Molecular Biology Event Category Butler Seminar Series