Emily Balskus, Harvard University

Deciphering Microbes and Microbiomes with Chemistry
Date
Nov 1, 2023, 12:00 pm1:00 pm
Location
Audience
Free and open to the university community and the public.

Speakers

Emily Balskus
Thomas Dudley Cabot Professor of Chemistry
Howard Hughes Medical Institute Investigator
Harvard University

Details

Event Description

The human body is colonized by trillions of microorganisms that exert a profound influence on human biology, in part by providing functional capabilities that extend beyond those of host cells. In particular, there is growing evidence linking chemical processes carried out by the microbial inhabitants of the gastrointestinal tract and cervicovaginal environment to both health and disease. However, we still do not understand the vast majority of the molecular mechanisms underlying this phenomenon. This talk will discuss my lab’s efforts to discover, characterize, and manipulate gut and vaginal microbial enzymes and metabolic pathways, including transformations that produce disease-associated microbial secondary metabolites. Gaining a molecular understanding of microbial biosynthetic pathways will not only enhance our ability to identify the genes encoding these activities in microbiome sequencing data but will also help to elucidate the mechanisms by which these organisms affect human biology. Ultimately, this work could enable efforts to improve health outcomes by manipulating gut and vaginal microbial metabolism.

Contacts
  • Cameron Myhrvold, Department of Molecular Biology
  • John Brooks II, Department of Molecular Biology
Event Category
Butler Seminar Series