Introduction to Genomics and Computational Molecular Biology

Subject associations
COS 551 / MOL 551 / QCB 551
Term
Fall 2024
Instructors
Joshua Akey
Mona Singh
Registrar description

This interdisciplinary course provides a broad overview of computational and experimental approaches to decipher genomes and characterize molecular systems. We focus on methods for analyzing "omics" data, such as genome and protein sequences, gene expression, proteomics and molecular interaction networks. We cover algorithms used in computational biology, key statistical concepts (e.g., basic probability distributions, significance testing, multiple hypothesis correction, data evaluation), and machine learning methods which have been applied to biological problems (e.g., hidden Markov models, clustering, classification techniques).