diSPIM is a flexible and easy-to-use implementation of Selective Plane Illumination Microscopy (SPIM) that allows for dual views (d) of the sample while mounted on an inverted (i) microscope. 
Capable of acquiring data down to 300 nm isotropic resolution.  488 and 561 lasers.  10, 20, and 40X optics.

Best Application/s:

Thinner samples, less than 100 um. Monolayers.  Smaller embryos.