The Electron Microscopy (EM) Core Facility is administered and supported by the Department of Molecular Biology in collaboration with the University’s Imaging & Analysis Center (IAC). We provide technical consultation and operational training for every aspect of biological EM sample preparation and data acquisition and analysis, including single-particle cryoEM structure determination.
Sample preparation equipment is located in Moffett Hall, Room 113. In addition to cryo-EM grid preparation via plunge freezing, we support other sample preparation methods including negative staining, immuno-labeling, and conventional and freeze-substitution embedding/sectioning.
We are open to all Princeton faculty, staff, and students, as well as to off-campus investigators and users. Training in sample preparation and EM operation is scheduled through the IAC training website. Those wishing to initiate an EM-based project are encouraged to contact the facility manager to discuss their needs and design a plan.