@article{2948,
  keywords = {Mechanical Phenomena, Ion Channels, Membranes},
  author = {Benedikt Sabass and Howard Stone},
  title = {Role of the Membrane for Mechanosensing by Tethered Channels.},
  abstract = { <p>Biologically important membrane channels are gated by force at attached tethers. Here, we generically characterize the nontrivial interplay of force, membrane tension, and channel deformations that can affect gating. A central finding is that minute conical channel deformation under force leads to significant energy release during opening. We also calculate channel-channel interactions and show that they can amplify the force sensitivity of tethered channels.</p> },
  year = {2016},
  journal = {Phys Rev Lett},
  volume = {116},
  pages = {258101},
  month = {2016 Jun 24},
  issn = {1079-7114},
  doi = {10.1103/PhysRevLett.116.258101},
  language = {eng},
}