@article{2621,
  keywords = {Animals, RNA, Messenger, Motor Activity, Caenorhabditis elegans Proteins, Amyotrophic Lateral Sclerosis, Frontotemporal Lobar Degeneration, Hydrogels, Phase Transition, RNA-Binding Protein FUS},
  author = {Shana Elbaum-Garfinkle and Clifford Brangwynne},
  title = {Liquids, Fibers, and Gels: The Many Phases of Neurodegeneration.},
  abstract = { <p>Recent advances suggest that phase transitions of proteins into liquid or hydrogel states could underlie pathological protein aggregation associated with neurodegenerative disease. In a recent issue of Neuron, Murakami et al. (2015) demonstrate that ALS-associated FUS mutations abrogate the reversibility of condensed liquids and/or hydrogels, leading to neurotoxicity in C. elegans.</p> },
  year = {2015},
  journal = {Dev Cell},
  volume = {35},
  pages = {531-532},
  month = {2015 Dec 07},
  issn = {1878-1551},
  doi = {10.1016/j.devcel.2015.11.014},
  language = {eng},
}