Major Requirements

A revised curriculum for MOL majors will go into effect in the fall of 2015. The new requirements will apply to the class of 2019. Changes for the classes of 2017 and 2018 are shown by class.

Prerequisites

  • MOL 214 or 215, completed with a grade of C or better
  • CHM 201/207 and CHM 202, or one unit of chemistry AP credit plus CHM 202 or 215, or two units of chemistry AP credit

An alternate path into the department is through the Integrated Science curriculum.

General Requirements

The following courses are required:

  • Organic Chemistry CHM 303 & 304/304B, or ISC 335
    Courses taken at other institutions can be used toward fulfillment of the chemistry requirements with approval from the Department of Chemistry.  The organic chemistry requirement must be completed before the beginning of the junior year.
  • Quantitative  Students without AP credit in calculus can satisfy the quantitative requirement for the MOL major by taking SML 201 (recommended), ORF 245, or NEU 314 and either COS 126 (recommended) or MAT 103. For students with AP credit in calculus, the quantitative requirement for the MOL major can be met by taking SML 201 (or an approved alternative) and either COS 126 (recommended) or a higher-level math course.
    Neither AP credit nor courses taken at other institutions can substitute for SML 201. Courses in computer science or mathematics taken at another institution can be substituted for the second required course, if approved by the corresponding department.
  • Physics PHY 108 (strongly recommended), or PHY 103 & 104, or PHY 101 & 102. PHY 108 is a one-semester, biologically oriented alternative to the traditional full-year sequences. Pre-medical students needing two semesters of physics can combine PHY 108 with PHY 101 or PHY 103. Neither AP credit nor courses taken at other institutions can be used toward the fulfillment of the physics requirement.

Department Core Courses

The following departmental core courses are required and, except under very special circumstances, must be taken before senior year:

  • MOL 342 Genetics
  • MOL 345 Biochemistry
  • MOL 348 Cell & Developmental Biology 
  • MOL 350 Laboratory in Molecular Biology

All four departmental core courses count toward the eight required departmentals. No substitutions are allowed except in the case of Integrated Science courses and study abroad which, if it entails intensive research and with advanced permission, can substitute for MOL 350. Note that MOL 345 may be taken concurrently with CHM 304/304B.

Other Departmentals

All students must take a total of at least eight departmentals. In addition to the four departmental core courses, students must take at least one 300, 400, or 500-level course with MOL as the primary listing. The remaining three departmentals can be chosen from among all 300-or-higher-level MOL, MOL-crosslisted, or other approved courses. Note that CHM 303, 304/304B, and ISC 335 qualify as departmentals. Only courses taken at Princeton count as departmentals; there are no exceptions to this rule.


Any course that is a prerequisite, requirement, or departmental must be taken for a letter grade (no P/D/F).


Integrated Science Curriculum

  • ISC 231-234 (a full-year, double-credit course) taken in the freshman year offers an alternative to the combination of MOL 214/215, CHM 201 & 202, COS 126, and PHY 103 & 104.
  • ISC 335 offers an alternative to CHM 303 and CHM 304/304B.
  • Students cannot receive credit for both an ISC course and its alternative. For full course descriptions and more information, see the Integrated Science website.

Study Abroad (fall semester junior year)

Juniors who wish to study abroad must fulfill chemistry requirements, and if possible MOL 345, beforehand.

While abroad, students must complete the equivalent of the fall semester junior paper. This requirement may be fulfilled by completing an independent scientific literature reading program, including weekly communication with a Molecular Biology faculty member and written reports, while abroad. Alternatively, students may join a journal club in a research laboratory abroad, with close monitoring by a Molecular Biology faculty member.

Study abroad that entails intensive laboratory research can, with advance permission, substitute for MOL 350. None of the other departmental core courses may be completed abroad.

Class of 2018

For those disciplines in which requirements have been changed (Physics, Math, Ecology & Evolutionary Biology), students can fulfill either the new OR old requirements (both are listed below):

  • PHY 108 (with or without PHY 101)
    -OR-
    PHY 101 & 102, or PHY 103 & 104
  • SML 201 (or an approved alternative), and COS 126 (recommended) or MAT 103 (students without calculus AP credit) or a higher-level math course (students with calculus AP credit)
    -OR-
    MAT 103 plus one additional semester of calculus or statistics or computer science
  • EEB 211 (or AP credit plus one 300-level EEB course) is no longer required
  • Math and physics requirements may still be satisfied with advanced placement and/or summer courses at other universities (within University guidelines).

    Departmentals: Students in the class of 2018 should follow the new requirements for departmental course credit:

    All students must take a total of at least eight departmentals. In addition to the four departmental core courses, students must take at least one 300, 400, or 500-level course   with MOL as the primary listing. The remaining three departmentals can be chosen from among all 300-or-higher-level MOL, MOL-crosslisted, or other approved courses

    Note that CHM 303, CHM 304/304B, and ISC 335 qualify as departmentals. Only courses taken at Princeton count as departmentals; there are no exceptions to this rule. 

    Class of 2017

    For those disciplines in which requirements have been changed (Physics, Math, Ecology & Evolutionary Biology), students can fulfill either the new OR old requirements (both are listed below):

    • PHY 108 (with or without PHY 101)
      -OR-
      PHY 101 & 102, or PHY 103 & 104
    • SML 201 (or an approved alternative), and COS 126 (recommended) or MAT 103 (students without calculus AP credit) or a higher-level math course (students with calculus AP credit)
      -OR-
      MAT 103 plus one additional semester of calculus or statistics or computer science
    • EEB 211 (or AP credit plus one 300-level EEB course) is no longer required

    Math and physics requirements may still be satisfied with advanced placement and/or courses at other universities (within University guidelines).