MOL 448 Chemistry, Structure, and Structure-Function Relations of Nucleic Acids**
The chemistry and structure of mononucleotides, oligonucleotides, and polynucleotides and their helical complexes as a basis for understanding and predicting the structures and structure-function relations of naturally occurring DNAs and RNAs. Related functions may include fidelity of DNA replication, mutagenic mechanisms, molecular evolution, telomeres, recently discovered RNA functions, structure of the genetic code.
Prerequisite: General chemistry and one semester of organic chemistry. Open to juniors, seniors, graduate students in Molecular Biology, Chemistry, EEB, Physics and Bioengineering. Others by permission of the instructor.