Genome Sequencing Fishes out Longevity Genes.

TitleGenome Sequencing Fishes out Longevity Genes.
Publication TypeJournal Article
Year of Publication2015
AuthorsLakhina, V, Murphy, CT
JournalCell
Volume163
Issue6
Pagination1312-3
Date Published2015 Dec 03
ISSN1097-4172
KeywordsAnimals, Biological Evolution, Female, Humans, Killifishes, Male, Sex Chromosomes
Abstract

Understanding the molecular basis underlying aging is critical if we are to fully understand how and why we age-and possibly how to delay the aging process. Up until now, most longevity pathways were discovered in invertebrates because of their short lifespans and availability of genetic tools. Now, Reichwald et al. and Valenzano et al. independently provide a reference genome for the short-lived African turquoise killifish, establishing its role as a vertebrate system for aging research.

DOI10.1016/j.cell.2015.11.040
Alternate JournalCell
PubMed ID26638067