The Biochemical Evolution of Protein Complexes.

TitleThe Biochemical Evolution of Protein Complexes.
Publication TypeJournal Article
Year of Publication2016
AuthorsGreco, TM, Cristea, IM
JournalTrends Biochem Sci
Volume41
Issue1
Pagination4-6
Date Published2016 Jan
ISSN0968-0004
KeywordsAnimals, Evolution, Molecular, Humans, Multiprotein Complexes, Protein Interaction Maps
Abstract

<p>Over the past decade, it became evident that proteins perform critical functions as components of specialized macromolecular complexes. Here, we discuss a recent study by Wan and colleagues, which highlights the significance of protein complexes by studying their conservation in organisms separated by up to a billion years of evolution.</p>

DOI10.1016/j.tibs.2015.11.007
Alternate JournalTrends Biochem. Sci.
PubMed ID26682499
PubMed Central IDPMC4706493
Grant ListR01 GM114141 / GM / NIGMS NIH HHS / United States
R01 HL127640 / HL / NHLBI NIH HHS / United States
GM114141 / GM / NIGMS NIH HHS / United States
HL127640 / HL / NHLBI NIH HHS / United States