Alert response to motion onset in the retina.

TitleAlert response to motion onset in the retina.
Publication TypeJournal Article
Year of Publication2013
AuthorsChen, EY, Marre, O, Fisher, C, Schwartz, G, Levy, J, da Silveira, RAzeredo, da Silviera, RAzeredo, Berry, MJ
JournalJ Neurosci
Volume33
Issue1
Pagination120-32
Date Published2013 Jan 2
ISSN1529-2401
KeywordsAction Potentials, Ambystoma, Animals, Attention, Motion, Motion Perception, Retina, Retinal Ganglion Cells
Abstract

<p>Previous studies have shown that motion onset is very effective at capturing attention and is more salient than smooth motion. Here, we find that this salience ranking is present already in the firing rate of retinal ganglion cells. By stimulating the retina with a bar that appears, stays still, and then starts moving, we demonstrate that a subset of salamander retinal ganglion cells, fast OFF cells, responds significantly more strongly to motion onset than to smooth motion. We refer to this phenomenon as an alert response to motion onset. We develop a computational model that predicts the time-varying firing rate of ganglion cells responding to the appearance, onset, and smooth motion of a bar. This model, termed the adaptive cascade model, consists of a ganglion cell that receives input from a layer of bipolar cells, represented by individual rectified subunits. Additionally, both the bipolar and ganglion cells have separate contrast gain control mechanisms. This model captured the responses to our different motion stimuli over a wide range of contrasts, speeds, and locations. The alert response to motion onset, together with its computational model, introduces a new mechanism of sophisticated motion processing that occurs early in the visual system.</p>

DOI10.1523/JNEUROSCI.3749-12.2013
Alternate JournalJ. Neurosci.
PubMed ID23283327
PubMed Central IDPMC3711149
Grant ListR01 EY017934 / EY / NEI NIH HHS / United States
EY017934 / EY / NEI NIH HHS / United States