Campbell Awarded NSERC Fellowship
Tracey Campbell, a postdoctoral fellow in Manuel Llinas' laboratory, was awarded the National Sciences and Engineering Research Council of Canada (NSERC) postdoctoral fellowship for her research proposal Investigating the role of ApiAP2 proteins as transcription factors during the red blood cell cycle of the malaria parasite Plasmodium falciparum.
The parasite that causes malaria has a complex lifecycle with three developmental stages: the mosquito, the human liver and human red blood cells. Expression of genes and proteins necessary for survival and infection are precisely coordinated during each of these developmental stages, but very little information is available regarding how this is achieved. The focus of Tracey's research is on the control of gene expression in this parasite, with a goal of identifying the factors responsible and at what stage of the infectious cycle they function in. Specifically the focus will be on a set of recently identified putative transcriptional regulators, the Apicomplexan AP2 (ApiAP2) proteins, and their potential role in the highly coordinated regulation of parasite development.