Engel Awarded Pew Fellowship
Esteban Engel, a postdoctoral fellow in Enquist lab, was awarded the first PEW postdoctoral fellowship award for our Department. The Pew Latin American Fellows Program in the Biomedical Sciences supports young biomedical scholars from Central and South America to advance research in their countries. The fellowship goal is to further the scientific knowledge, promote exchange and collaboration between investigators in the U.S. and Latin America, and advance research in Latin America.
Esteban is interested in the HSV-1 clinical strain H129 because it is the only virus of any known type to egress exclusively in the anterograde direction. The retrograde spread from post-synaptic neuron to pre-synaptic neuron is impaired in this strain. There is no clear explanation for this unique phenotype and Esteban’s aim is to demonstrate the relationship between the phenotype of H129 strain and specific mutations in viral genes. Additionally, he will produce recombinants of this and other HSV-1 strains expressing fluorescent proteins with enhanced tracing capabilities.