Korpal Wins DOD Breast Cancer Award
Manav Korpal, a third year graduate student in the Kang lab, was awarded a pre-doctoral fellowship from the Department of Defense Breast Cancer Research Program. This three-year award will fund his proposal titled “A mouse model for in vivo detection and disruption of TGF-beta signaling in breast cancer metastasis”. The major goal of the project is to utilize a novel mouse model developed by the lab—which allows in vivo detection of active TGF-beta signaling in tumor cells— to assess the dynamic role of this signaling pathway in promoting breast cancer metastasis to various organs. In addition, this mouse model will also serve as a powerful tool with which to evaluate the therapeutic efficacy of various inhibitors of the TGF-beta pathway. Manav Korpal has also previously received a pre-doctoral fellowship from the Natural Sciences and Engineering Research Council of Canada for his first two years of graduate study at Princeton.