Enquist Lab

Enquist Lab Members

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Principal Investigator

Lynn W. Enquist
Lynn W. Enquist
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Research Interest:  Genetics and molecular biology of DNA viruses with a special emphasis on neurotropic alpha herpes viruses. Lynn W. Enquist Biography »

Curriculum Vitaepdf-icon-25x25


Postdoctoral Fellows

Jens Bernhard
Jens-Bernhard Bosse
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Research Interest: How herpes viruses remodel the host nucleus and how they facilitate capsid egress from the nucleus.


Esteban
Esteban Engel
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Research Interest: Studying the mechanisms of herpes viruses pathogenesis anddeveloping new viral strains with enhanced tracing capabilities.


Ian Hogue
Ian Hogue
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Research Interest: Studying the cell biological mechanisms of herpesvirus egress/exocytosis.


Orkide
Orkide Koyuncu
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Research Interest: Orkide is aiming to better understand the molecular mechanisms of the cross-talk between alpha-herpesviruses and host neurons during viral infection. One of the most interesting features of neurons is the presence of local protein synthesis machinery in axons; far away from the cell body. Those locally translated proteins regulate growth cone navigation and integrity during development, regeneration and retrograde communication with the cell body in adult neurons. She is particularly interested in revealing how axonal RNA/protein dynamics are affected during viral infection and whether viruses modulate or utilize such machinery in neurites for efficient transport and spread.


Karen Lancaster
Karen Lancaster
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Research Interest: Karen is interested in the viral spread from the periphery to the central nervous system. Specifically, elucidating the mechanisms of trans-synaptic spread and the neuronal perturbations that accompany this unique cell to cell infection. She is interested in understanding the role of electrical coupling, increased action potential firing, altered intracellular calcium and mitochondrial dynamics from both host and viral standpoints. Additionally, Karen plans to further develop these findings to understand the long term consequences of viral infection on neuronal circuits after the acute phase of infection has been resolved.

 

Julian
Julian Scherer
 
Research Interest:  Julian is interested in microtubule based transport of herpes viruses during entry and egress and the role of molecular motors in infection.

Graduate Students

Hao
Oliver Hao Huang
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Ren
Ren Song

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Research Interest:  Ren is interested in the molecular mechanisms of PRV retrograde infection in peripheral nervous system neurons under the influence of host immune responses. Her current research focuses on how neuronal axons respond to pro-inflammatory cytokines and how these responses affect the retrograde transport and replication of PRV.



Undergraduates

 
Jihad Al-Jabban
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Brendan Wu
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Lab Manager

Halina
Halina Staniszewska Goraczniak
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Administrative Assistant

Matt
Matthew Montondo
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P (609) 258-2664