Faculty & Research
Structural Biology

Structural Biology

Structural Biology Research

Members of Princeton's vibrant structural biology community—students, postdocs, and faculty—make use of a wide array of cutting-edge methods to gain insight into biological structure and mechanism. Some examples of the approaches being used, and in some cases developed, at Princeton include x-ray crystallography, electron microscopy, mass spectrometry, NMR spectroscopy, super-resolution optical microscopy, single-molecule methods, and computational modeling. These tools are being applied to biological problems ranging from protein folding and design, to signal transduction, to intracellular trafficking. Structural biology is an intrinsically interdisciplinary activity; Princeton provides a supportive and exceptionally collegial environment for students to receive training in these areas while, at the same time, contributing to fundamental discoveries about form and function in the biological world.

Faculty in Structural Biology Research

Bonnie L. Bassler

Bonnie L.
Bassler

SQUIBB PROFESSOR/
chair

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phone (609) 258-2857

Research: Cell-to-cell communication in bacteria

Areas of Research: Biochemistry, Computation & Modeling, Genetics, Microbiology & Virology, Structural Biology

Bassler
Research Lab

locationLewis Thomas Lab, 329
phoneLab (609) 258-2864

 


Jannette Carey

Jannette
Carey

CHEMISTRY

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Phone (609) 258-1631

Research: Biophysical chemistry: molecular origins of macromolecular affinity and specificity

Areas of Research: Biochemistry, Biophysics, Computation & Modeling, Genomics, Structural Biology

Carey
Research Lab

locationFrick Lab, 360
 


Michael Hecht

Michael H.
Hecht

Chemistry

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Phone (609) 258-2901

Research: Protein folding; design of novel proteins; molecular determinants of Alzheimer's disease

Areas of Research: Biochemistry, Biophysics, Structural Biology

Hecht
Research Lab

locationFrick Lab, 330
Phone Lab (609) 258-2901


Fred Hughson

Frederick M. Hughson

Professor

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Phone (609) 258-4982

Research: Structural cell biology

Areas of Research: Biochemistry, Biophysics, Cell Biology, Microbiology & Virology, Structural Biology

Hughson
Research Lab

locationSchultz Lab, 215
Phone Lab (609) 258-5069


Alexei Korennykh

Alexei
Korennykh

Assistant Professor

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Phone (609) 258-6071

Research: Structural biology and mechanisms of signal transduction in stress and immune responses

Areas of Research: Structural Biology, Biochemistry, Biophysics, Cancer, Cell Biology

Korennykh
Research Lab

locationSchultz Lab, 216
Phone Lab (609) 258-6071


Tom Muir

Tom
Muir

Chemistry

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Phone (609) 258-5778

Research: Organic Chemistry, Biochemistry and Cell Biology: Investigating the physiochemical basis of protein function in complex systems of biomedical interest with new chemical biology technologies

Areas of Research: Biochemistry, Chemical Biology, Structural Biology

locationFrick Lab, 325


 

Sabine Petry

Sabine
Petry

Assistant Professor

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Research: Molecular architecture and function of the microtubule cytoskeleton

Areas of Research: Biochemistry, Biophysics, Cancer, Cell Biology, Structural Biology

Petry
Research Lab

locationSchultz Lab, 415


Mona Singh

Mona
Singh

Computer Science

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Phone (609) 258-2087

Research: Computational molecular biology

Areas of Research: Computation & Modeling, Genomics, Structural Biology

Singh
Research Lab

locationComputer Science Bldg, 420


Jeffry B. Stock

Jeffry B.
Stock

Professor

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Phone (609) 258-6111

Research: Membrane receptors and signal transduction

Areas of Research: Biochemistry,
Biophysics, Microbiology &  Neuroscience, Structural Biology

Stock
Research Lab

locationLewis Thomas Lab, 148
Phone Lab (609) 258-6112


Samuel Wang

Samuel S.
Wang

Associate Professor

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Phone (609) 258-0388

Research: Information processing and learning in mammalian brains

Areas of Research: Biophysics, Chemical Biology, Computation & Modeling, Development, Evolution, Genetics, Neuroscience, Policy, Structural Biology

Wang
Research Lab

locationPrinceton Neuroscience Institute, A85
Phone Lab (609) 258-0374

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Lewis Thomas Laboratory at Princeton University

119 Lewis Thomas Laboratory
Washington Road, Princeton, NJ  08544-1014

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Fax: (609) 258-3980
Website:  molbio.princeton.edu