Biochemistry
Biochemistry Research
Biochemistry is the foundation of all cellular processes and systems. Biochemical processes account for the functions of all cellular components, from proteins to lipids and metabolites, and the formation of complex networks that make a cell or system work. Encompassing a multitude of modern techniques and approaches, the field of biochemistry has a powerful diversity that can provide a detailed, mechanistic view of cellular pathways. With a long-standing tradition in biochemistry, Princeton reflects this diversity through the multidisciplinary span of our research. State-of-the-art mass spectrometry and X-ray crystallography are among the techniques utilized by our scientists to characterize cellular environments and pathways in health and disease. Our collaborative department is at the forefront of proteomics and metabolomics, which are integrated with genomics, microbiology, cancer and developmental biology, providing an opportunity for systems biology training at the interface between cellular biology and human disease.
Faculty in Biochemistry
Bonnie L.
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Research: Cell-to-cell communication in bacteria Areas of Research: Biochemistry, Computation & Modeling, Genetics, Microbiology & Virology, Structural Biology |
Bassler
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Lisa M.
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Research: Immune proteins in the formation, function, and modification of neuronal connectivity Areas of Research: Biochemistry, Biophysics, Cell Biology, Development, Neuroscience |
Boulanger
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Jannette
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Research: Biophysical chemistry: molecular origins of macromolecular affinity and specificity Areas of Research: Biochemistry, Biophysics, Computation & Modeling, Genomics, Structural Biology |
Carey
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Ileana M.
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Research: Proteomic-Genomic approaches to chromatin and its modulation by viruses Areas of Research: Biochemistry, Genetics, Genomics, Microbiology & Virology |
Cristea
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Dorothea
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Research: Signaling and metabolic functions of second messengers Areas of Research: Biochemistry, Cell Biology, Genetics, Genomics |
Fiedler
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S. Jane
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Research: Regulation of viral and cellular gene expression in adenovirus-infected cells Areas of Research: Biochemistry, Cell Biology, Microbiology & Virology |
Flint
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Jacques R.
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Research: A new approach to gene therapy; cytogenetic probes for amplified cancer-relevant genes; physical-chemical studies of nucleic acids; mutagenic mechanisms; molecular mechanisms Areas of Research: Biochemistry, Biophysics, Cancer, Cell Biology, Evolution |
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Benjamin
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Research: Quantitative mass spectrometry based proteomics for analysis of eukaryotic chromatin structure and function Areas of Research: Biochemistry |
Garcia
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Elizabeth R.
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Research: RNA localization and translational regulation during development in Drosophila Areas of Research: Biochemistry, Cell Biology, Development, Genetics |
Gavis
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Zemer
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Research: Bacterial cell biology: fundamentals of cytoskeletal dynamics, polarity, and mitosis Areas of Research: Biochemistry, Cell Biology, Development, Genetics, Microbiology & Virology |
Gitai
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Frederick M. HughsonProfessor
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Research: Structural cell biology Areas of Research: Biochemistry, Biophysics, Cell Biology, Microbiology & Virology, Structural Biology |
Hughson
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Michael H.
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Research: Protein folding; design of novel proteins; molecular determinants of Alzheimer's disease Areas of Research: Biochemistry, Biophysics, Structural Biology |
Hecht
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Yibin
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Research: Molecular mechanisms of cancer metastasis Areas of Research: Biochemistry, Cancer, Cell Biology, Development, Genetics, Genomics |
Kang
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Alexei
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Research: Structural biology and mechanisms of signal transduction in stress and immune responses Areas of Research: Structural Biology, Biochemistry, Biophysics, Cancer, Cell Biology |
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A. James
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Research: Protein engineering and chemical biology Areas of Research: Biochemistry, Biophysics, Microbiology & Virology |
Link
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Manuel
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Research: Molecular mechanisms of the malaria parasite Plasmodium falciparum Areas of Research: Biochemistry, |
Llinás
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Tom
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Research: Organic Chemistry, Biochemistry and Cell Biology: Investigating the physiochemical basis of protein function in complex systems of biomedical interest with new chemical biology technologies Areas of Research: Biochemistry, Chemical Biology, Structural Biology |
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Coleen T.
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Research: Molecular mechanisms of aging Areas of Research: Biochemistry, |
Murphy
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Mala
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Research: Olfactory and Auditory Perception in Drosophila Areas of Research: Biochemistry, |
Murthy
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Joshua
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Research: Towards a holistic understanding of cellular metabolism Areas of Research: Biochemistry, |
Rabinowitz
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Jean E. SchwarzbauerProfessor
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Research: Extracellular matrix regulation of cell functions Areas of Research: Biochemistry, Cancer, Cell Biology, Development, Genetics |
Schwarzbauer
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Thomas E.
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Research: Human cytomegalovirus replication and pathogenesis Areas of Research: Biochemistry, Cell Biology, Genetics, Genomics, |
Shenk
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Thomas J.
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Research: Protein targeting and signal transduction Areas of Research: Biochemistry, Cell Biology, Genetics, Microbiology & Virology |
Silhavy
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Jeffry B.
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Research: Membrane receptors and signal transduction Areas of Research: Biochemistry, |
Stock
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Virginia A.
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Research: DNA replication and chromosome structure in yeast; telomeres; trinucleotide repeats Areas of Research: Biochemistry, Cancer, Cell Biology, Genetics, Microbiology & Virology |
Zakian
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