Sean Crosson (University of Chicago)
MolBio Seminar Series
Sean Crosson grew up in Grayson County, Texas. He received his undergraduate degree in biology in 1996 from Earlham College and his Ph.D. in biochemistry/biophysics from the University of Chicago in 2002. From 2003 to 2005 he was a postdoctoral fellow at Stanford University School of Medicine, where he began to investigate mechanisms bacterial sensory transduction. He is currently Associate Professor of Biochemistry and Molecular Biology at the University of Chicago. Since joining the Chicago faculty in 2006, he has developed an interdisciplinary research program that is focused on understanding regulatory mechanisms that control bacterial cell physiology and virulence. His studies center on the model system Caulobacter crescentus and the related human pathogen Brucella abortus, which is the causative agent of the global zoonotic disease known as brucellosis.
Integrated control of bacterial cell adhesion and stress physiology
Bacteria live in almost every conceivable niche on the planet, yet we have limited understanding of which chemical and physical features of natural environments are relevant to bacterial biology. Our group is working to identify new environmental signals and to understand the molecular, genetic, and cellular mechanisms that underlie the ability of cells to adapt to chemically- and physically-complex environments. This presentation will focus on our recent functional and structural analyses of a conserved photosensory system in the alphaproteobacteria that regulates processes including stress physiology, cell-surface adherence, and chronic mammalian infection.
Free and open to the university community and the public