Princeton University Molecular Biology - Molecular Biology Calendar of Events http://molbio.princeton.edu Sat, 25 Oct 2014 13:46:28 -0400 Joomla! - Open Source Content Management en-gb Molecular Biology Career Symposium 2014 http://molbio.princeton.edu/events/all/event/348-molecular-biology-career-symposium-2014 http://molbio.princeton.edu/events/all/event/348-molecular-biology-career-symposium-2014 Location: Lewis Thomas Lab, 003 - Princeton
Category: Symposia
Date: Tue, Sep 09, 2014 - Tue, Sep 09, 2014
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Overview

Career Symposium

SAVE THE DATE

The Career Symposium aims to expose current graduate students and post-docs to a diverse set of possible careers available to PhDs in biology. Distinguished professionals, including former alumni of the Princeton Molbio graduate program, will be invited to speak about their experiences in academia, education, business, policy, and communication. Beyond the scheduled talks, the full-day program schedule will enable ample opportunities for questions and networking for all attendees. This is the 2nd career symposium initiated by the department, and we encourage all students and post-docs to participate.

Register Now
 

Schedule

8:45 am Opening remarks — Shirley Tilghman
9:00-10:15 am Session I  Business Technology
9:00-9:15 am Adam Evertts, LifeSci Advisors
9:15-9:30 am Courtney Williams, Regeneron
9:30-9:45 am Debbie Yu, Labrador Advisors
9:45 -10:00 am Patrice Jean, Kenyon and Kenyon
10:00-10:15 am Question and Answer
10:15-10:45 am Coffee break
10:45-11:45 am Session II — Science Education
10:45-11:00 am Christine Hunter, Abington Friends School
11:00-11:15 am Lisa Taneyhill, University of Maryland
11:15-11:30 am Hal White, University of Delaware
11:30-11:45 am Question and Answer
12:00-1:00 pm Lunch with graduate students and post docs
1:00-1:15 pm Amy Pszczolkowski — The next steps - how Career Services can help
1:15-2:15 pm Session III — Policy
1:15-1:30 pm Scott Steele, University of Rochester
1:30-1:45 pm Michael Ingerson-Mahar, Department of Defense
1:45-2:00 pm Christopher Chyba, Princeton University
2:00 - 2:15 pm Question and Answer
2:15-2:45 am Coffee break
3:00-4:00 pm Session IV — Science Communication Support
3:00-3:15 pm Jill Harper, National Institute of Health
3:15-3:30 pm Carmen Drahl, American Chemical Society
3:30-3:45 pm Adam Ruben, Sanaria Inc.
3:45-4:00 pm Question and Answer
4:00-4:30 pm Tom Vogt  Perspectives on careers open to PhDs
4:45 pm Reception in Carl Icahn building
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Symposia Mon, 27 Jun 2011 12:24:03 -0400
Molecular Biology Retreat 2014 http://molbio.princeton.edu/events/all/event/366-retreat-2014 http://molbio.princeton.edu/events/all/event/366-retreat-2014 Location: Frick Chemistry Laboratory - Princeton
Category: Retreat
Date: Fri, Oct 10, 2014 - Sat, Oct 11, 2014
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Invitation Only

October 10-11, 2014

DESCRIPTION
 
The retreat is a wonderful opportunity for our expansive and diverse department to engage scientifically, form collaborations, and interact in an informal setting. It is also a part of our graduate program, giving graduate students and post-docs the chance to present their research in the form of posters and talks.
 
 
Co-chairs

Alexander Ploss and Sabine Petry
Co-chairs, Mol Bio Retreat

Audience

Invitation Only. Graduate Students, Postdocs, Faculty and Staff

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Retreat Tue, 30 Jul 2013 14:25:56 -0400
John Quackenbush (Harvard) http://molbio.princeton.edu/events/all/event/392-quackenbush http://molbio.princeton.edu/events/all/event/392-quackenbush Location: Carl Icahn Lab, 101 - Princeton
Category: Quantitative & Computional Biology
Date: Mon, Oct 20, 2014 - Mon, Oct 20, 2014
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Solving the Personalized Medicine Puzzle

Since the introduction of second-generation sequencing technologies in 2007, the cost and time required to sequence a genome have fallen dramatically. As DNA sequencing increasingly becomes a commodity, biomedical research is rapidly evolving from a purely laboratory science to an information science in which the winners in the race to cure disease are likely to be those best able to collect, manage, analyze, and interpret data. Here I will provide an overview of the approach we have been developing to deal with the challenge of personal genomic data, including integrative approaches to data analysis and the creation of data portals focused on addressing the most common use cases presented by different user constituencies. By effectively collecting genomic and clinical data and linking information available in the public domain, we have made significant advances in uncovering the cellular networks and pathways that underlie human disease, building predictive models of those networks that may help to direct therapies, and in understanding the distinct requirements of research and medical applications.

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Quantitative & Computional Biology Thu, 25 Sep 2014 10:27:14 -0400
Olga Vitek (Purdue) http://molbio.princeton.edu/events/all/event/384-vitek http://molbio.princeton.edu/events/all/event/384-vitek Location: Carl Icahn Lab, 101 - Princeton
Category: Quantitative & Computional Biology
Date: Mon, Nov 03, 2014 - Mon, Nov 03, 2014
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Quantitative & Computional Biology Thu, 25 Sep 2014 10:27:14 -0400
Ahmet Yildiz (UC, Berkeley) http://molbio.princeton.edu/events/all/event/357-yildiz http://molbio.princeton.edu/events/all/event/357-yildiz Location: Lewis Thomas Lab, 003 - Princeton
Category: Butler Seminar Series
Date: Wed, Nov 05, 2014 - Wed, Nov 05, 2014
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Butler Seminar Series

Speaker
Ahmet
Ahmet Yildiz, Ph.D.
University of California, Berkeley

Ahmet Yildiz is Assistant Professor of Biochemistry, Biophysics and Structural Biology at the University of California, Berkeley.  Yildiz laboratory combines molecular biology and biophysical techniques to understand mechanisms that underlie the cellular organization and motility. Single molecule imaging enables direct observation of molecular motions, time courses of reactions and heterogeneity in subpopulations of the proteins. One major focus is to understand how microtubule motors work individually and how their interaction play a key role in intracellular transport and organismal motility. We are also using superresolution imaging techniques to visualize high order structures of telomeric DNA in human cells.

Seminar Topic

 
The Mechanism of Cytoplasmic Dynein Motility

Cytoplasmic dynein is an AAA+ motor responsible for intracellular cargo transport and force generation tasks along microtubule filaments. The mechanism of dynein motility remains unclear, due to its large size (2.6 MDa) and the complexity of its structure. Using a variety of single molecule imaging and manipulation methods, we observed that dynein heads move independently along the MT, in contrast to hand over hand movement of kinesins and myosin. Dynein utilizes two distinct stepping mechanisms depending on the separation between the heads. Nucleotide-dependent release is inhibited by the tension on the linker at high separations. The two heads of a dynein dimer share the load to resist larger opposing forces. The minus-end directionality is determined by the asymmetric binding and release properties of the microtubule binding interface. Reversing the asymmetry of the microtubule binding domain resulted in plus-end directed motility. Finally, the AAA3 site is a secondary site of ATP hydrolysis that acts as a molecular switch to repurpose dynein for cargo transporting and microtubule anchor functions. On the basis of these measurements, we propose a quantitative model that describes the basis of dynein processivity, directionality and force generation.
 

Research lab


http://research.physics.berkeley.edu/yildiz/
 
 

Audience

Free and open to the university community and the public

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Butler Seminar Series Mon, 18 Aug 2014 15:09:18 -0400
Frank Tong (Vanderbilt) http://molbio.princeton.edu/events/all/event/377-tong http://molbio.princeton.edu/events/all/event/377-tong Location: PNI, Room A32 -
Category: Neuroscience Seminar Series
Date: Thu, Nov 06, 2014 - Thu, Nov 06, 2014
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Neuroscience Seminar Series

Speaker
tong
Frank Tong, Ph.D.
Vanderbilt University

Seminar Topic

 
TBA
 

research Lab


http://www.psy.vanderbilt.edu/tonglab/web/Home.html

Audience

Free and open to the university community and the public


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Neuroscience Seminar Series Mon, 18 Aug 2014 15:09:18 -0400
Michael Elbaum (Weizzman) http://molbio.princeton.edu/events/all/event/385-elbaum http://molbio.princeton.edu/events/all/event/385-elbaum Location: Carl Icahn Lab, 101 - Princeton
Category: Quantitative & Computional Biology
Date: Mon, Nov 10, 2014 - Mon, Nov 10, 2014
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Quantitative & Computional Biology Thu, 25 Sep 2014 10:27:14 -0400
Steven Leach (Johns Hopkins) http://molbio.princeton.edu/events/all/event/358-leach http://molbio.princeton.edu/events/all/event/358-leach Location: Lewis Thomas Lab, 003 - Princeton
Category: Butler Seminar Series
Date: Wed, Nov 12, 2014 - Wed, Nov 12, 2014
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MolBio Seminar Series

Speaker
Leach
Steven Leach, M.D.
Johns Hopkins University

Steven Leach is the David M. Rubenstein Chair and Director of the Rubenstein Center for Pancreatic Cancer Research at Memorial Sloan Kettering Cancer Center.  Prior to this, he served as the Paul K. Neumann Professor in Pancreatic Cancer at Johns Hopkins, where he was also Professor of Surgery, Oncology and Cell Biology.  Dr. Leach received his bachelor’s degree with high honors in Biology from Princeton University, where he currently serves as a member of the Board of Trustees.  He then completed medical school at Emory University, and clinical training at Yale and M.D. Anderson.  While at Yale, he pursued additional postdoctoral training in Cell Biology under the supervision of Fred Gorelick. Dr. Leach’s lab has a long track record of research productivity in the field of pancreatic tumor biology.  Dr. Leach’s group is credited with discovery of abnormal Notch pathway activation as an important driver of pancreatic tumorigenesis, development of the first zebrafish model of pancreatic cancer, identification of adult acinar cells as effective cells of origin for the initiation of pancreatic “ductal” neoplasia, and the recent identification of a hematopoietic-to-epithelial IL-17 signaling axis required for pancreatic cancer initiation. Together with additional studies of pancreatic developmental biology and pancreatic epithelial plasticity, work from the Leach Lab has contributed significantly to our understanding of early pancreatic cancer.

Seminar Topic

 
Learning about human pancreatic cancer from mouse and zebrafish embryos

By 2020, pancreatic cancer is slated to become the country’s second leading cause of cancer death.  However, the biology underlying pancreatic cancer initiation and progression remains poorly understood.  Using principles and techniques emanating from our studies of pancreatic development in both mouse and zebrafish, we have been able to gain important new insights into mechanisms of cellular plasticity underlying pancreatic cancer initiation, as well as additional signaling pathways required for pancreatic cancer progression. 
 

Audience

Free and open to the university community and the public

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Butler Seminar Series Mon, 18 Aug 2014 15:09:18 -0400
Tanja Kortemme (UCSF) http://molbio.princeton.edu/events/all/event/386-kortemme http://molbio.princeton.edu/events/all/event/386-kortemme Location: Carl Icahn Lab, 101 - Princeton
Category: Quantitative & Computional Biology
Date: Mon, Nov 17, 2014 - Mon, Nov 17, 2014
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Quantitative & Computional Biology Thu, 25 Sep 2014 10:27:14 -0400
Jo Handelsman (Yale) http://molbio.princeton.edu/events/all/event/359-handelsman http://molbio.princeton.edu/events/all/event/359-handelsman Location: Lewis Thomas Lab, 003 - Princeton
Category: Butler Seminar Series
Date: Wed, Nov 19, 2014 - Wed, Nov 19, 2014
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Butler Seminar Series

Speaker
jo handelsman
Jo Handelsman, Ph.D.
Yale University

Dr. Jo Handelsman is a Howard Hughes Medical Institute Professor and Frederick Phineas Rose Professor in the Department of Molecular, Cellular and Developmental Biology at Yale University. She received her Ph.D. in Molecular Biology from the University of Wisconsin-Madison in 1984 and she served on the faculty at the University of Wisconsin-Madison from 1985 until moving to Yale in 2010. Her research focuses on the genetic and functional diversity of microorganisms in soil, plant and insect gut communities. Handelsman’s lab is one of the pioneers of functional metagenomics, an approach to accessing the genetic potential of unculturable bacteria in environmental samples. Their studies using both culture-based and metagenomic analyses have led to discovery of novel antibiotics and determinants of antibiotic resistance and expanded understanding of multispecies interactions that enhance or diminish the health of host animals and plants.

Seminar Topic

 
TBA
 

Research lab


http://www.yale.edu/handelsmanlab/ 
 

Audience

Free and open to the university community and the public

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Butler Seminar Series Mon, 18 Aug 2014 15:09:18 -0400
John Murray (Penn) http://molbio.princeton.edu/events/all/event/387-murray http://molbio.princeton.edu/events/all/event/387-murray Location: Carl Icahn Lab, 101 - Princeton
Category: Quantitative & Computional Biology
Date: Mon, Nov 24, 2014 - Mon, Nov 24, 2014
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Quantitative & Computional Biology Thu, 25 Sep 2014 10:27:14 -0400
John Wikswo (Vanderbilt) http://molbio.princeton.edu/events/all/event/388-wikswo http://molbio.princeton.edu/events/all/event/388-wikswo Location: Carl Icahn Lab, 101 - Princeton
Category: Quantitative & Computional Biology
Date: Mon, Dec 01, 2014 - Mon, Dec 01, 2014
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Quantitative & Computional Biology Thu, 25 Sep 2014 10:27:14 -0400
Frank Sicheri (U of Toronto) http://molbio.princeton.edu/events/all/event/360-sicheri http://molbio.princeton.edu/events/all/event/360-sicheri Location: Lewis Thomas Lab, 003 - Princeton
Category: Butler Seminar Series
Date: Wed, Dec 03, 2014 - Wed, Dec 03, 2014
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Butler Seminar Series

Speaker
sicheri
Frank Sicheri, Ph.D.
University of Toronto

Dr. Frank Sicheri is a Professor in the Biochemistry at the University of Toronto. He received his Ph.D. from McMaster University in 1994.  His lab's research is directed at understanding protein kinase regulation with a focus towards the underlying structural mechanisms that imparts specificity to signaling function. Using x-ray crystallography, we seek to uncover the structural basis for catalytic switching, substrate recognition and down-stream phospho-regulatory mechanisms. In addition, the Sicheri lab is interested in uncovering the structure and function of novel effectors that impact on protein kinase function. These efforts have led our lab into the area of ubiquitin directed proteolysis. The lab's long-term goal is to make use of what they learn to develop drugs to treat human disease.

Seminar Topic

 
TBA
 

Research lab


http://www.mshri.on.ca/sicheri 

Audience

Free and open to the university community and the public

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Butler Seminar Series Mon, 18 Aug 2014 15:09:18 -0400
Nachum Ulanovsky (Weizmann Institute of Science) http://molbio.princeton.edu/events/all/event/378-ulanovsky http://molbio.princeton.edu/events/all/event/378-ulanovsky Location: PNI, Room A32 -
Category: Neuroscience Seminar Series
Date: Thu, Dec 04, 2014 - Thu, Dec 04, 2014
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Neuroscience Seminar Series

Speaker
Nachum
Nachum Ulanovsky, Ph.D.
Weizmann Institute of Science

Seminar Topic

 
TBA
 

research Lab


http://wws.weizmann.ac.il/neurobiology/labs/ulanovsky/

Audience

Free and open to the university community and the public


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Neuroscience Seminar Series Mon, 18 Aug 2014 15:09:18 -0400
Mansun Law (Scripps) http://molbio.princeton.edu/events/all/event/361-law http://molbio.princeton.edu/events/all/event/361-law Location: Lewis Thomas Lab, 003 - Princeton
Category: Butler Seminar Series
Date: Wed, Jan 21, 2015 - Wed, Jan 21, 2015
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Bulter Seminar Series

Speaker
law
Mansun Law, Ph.D.
The Scripps Research Institute

Dr. Mansun Law is Associate Professor of Immunology and Microbial Science at The Scripps Research Institute. He received his Ph.D. in Virology from the University of Oxford in 2001.  His lab's research focuses on challenges in understanding and generating protective antibodies to highly variable human viruses.

Seminar Topic

 
TBA
 

Research lab


http://www.scripps.edu/law

Audience

Free and open to the university community and the public

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Butler Seminar Series Mon, 18 Aug 2014 15:09:18 -0400
Melissa Moore (HHMI/UMass Medical School) http://molbio.princeton.edu/events/all/event/362-moore http://molbio.princeton.edu/events/all/event/362-moore Location: Lewis Thomas Lab, 003 - Princeton
Category: Butler Seminar Series
Date: Wed, Jan 28, 2015 - Wed, Jan 28, 2015
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Butler Seminar Series

Speaker
Melissa Moore
Melissa J. Moore, Ph.D.
University of Massachusetts Medical School

Dr. Moore is Professor and HHMI Investigator of Biochemistry and Molecular Pharmacology at the University of Massachusetts Medical School.  She received her B.S. degree in chemistry and biology from the College of William and Mary and her Ph.D. degree in biological chemistry from the Massachusetts Institute of Technology. She began working on RNA metabolism during her postdoctoral training with Phillip Sharp at MIT. Dr. Moore's honors include a Searle Scholars Award, a David and Lucile Packard fellowship, and the 2011 ASBMB William C. Rose Award. Research in her laboratory encompasses a broad array of post-transcriptional gene regulatory mechanisms involving RNA and RNA-protein complexes. Their research centers on pre-mRNA processing and large RNA-protein (RNP) complexes.  We study their basic structures and functions as well as their contributions to human disease.  Current areas of investigation include: (1) single molecule analysis of spliceosome assembly; (2) messenger RNP (mRNP) structure and function; (3) RNP egress by nuclear envelope budding; and (4) development of novel therapeutic approaches targeting RNA-based processes.  Enabling these studies, our research spans the disciplines of cell and molecular biology, biochemistry, chemical biology, biophysics and bioinformatics.

Seminar Topic

 
TBA
 

Research lab


http://labs.umassmed.edu/moorelab/Moore_Lab_Website/home.html

Audience

Free and open to the university community and the public

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Butler Seminar Series Mon, 18 Aug 2014 15:09:18 -0400
Joseph Mougous (U Washington) http://molbio.princeton.edu/events/all/event/363-mougous http://molbio.princeton.edu/events/all/event/363-mougous Location: Lewis Thomas Lab, 003 - Princeton
Category: Butler Seminar Series
Date: Wed, Feb 04, 2015 - Wed, Feb 04, 2015
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Butler Seminar Series

Speaker
mougous
Joseph Mougous, Ph.D.
University of Washington

Dr. Moore is Associate Professor of Microbiology at the University of Washington. Dr. Mougous performed his graduate studies at the University of California at Berkeley in the laboratory of Dr. Carolyn Bertozzi. His thesis focused on the biosynthesis and role in virulence of sulfated glycolipids produced by Mycobacterium tuberculosis. As a postdoctoral fellow in the laboratory of Dr. John Mekalanos at Harvard Medical School, Dr. Mougous studied protein secretion in Pseudomonas aeruginosa.

A major focus of the Mougous lab is to understand, from both mechanistic and functional perspectives, the type VI protein secretion system (T6SS). This pathway, which is present in hundreds of Gram-negative bacteria, is remarkable in that it can target its substrates–some of which are toxins–to eukaryotic or prokaryotic cells. Current projects in our lab aim to identify novel T6SS substrates and characterize their mechanism-of-action, develop a structure-function model for the T6SS, define the steps leading to activation of the system, and to investigate the impact of the system on bacterial pathogenesis and microbial ecology. The lab employs a diverse toolkit that ranges from animal models of disease to protein crystallography.

Seminar Topic

 
TBA
 

Research lab


http://faculty.washington.edu/mougous

Audience

Free and open to the university community and the public

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Butler Seminar Series Mon, 18 Aug 2014 15:09:18 -0400
Sreekanth Chalasani (UC, San Diego) http://molbio.princeton.edu/events/all/event/364-chalasani http://molbio.princeton.edu/events/all/event/364-chalasani Location: Lewis Thomas Lab, 003 - Princeton
Category: Butler Seminar Series
Date: Wed, Feb 11, 2015 - Wed, Feb 11, 2015
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Butler Seminar Series

Speaker
chalasani
Sreekanth Chalasani, Ph.D.
University of California, San Diego
Salk Institute for Biological Studies 

Dr. Sreekanth Chalasani is Assistant Professor of Molecular Neurobiology at the Salk Institute for Biological Studies, University of California, San Diego.  Dr. Chalasani received his B.S. from Osmania University, India and his Ph.D. from the University of Pennsylvania.   His lab's research focuses on how neural circuits decode environmental changes and drive behaviors. The lab uses the nematode, C. elegans and zebrafish as models to study brain functions.

Seminar Topic

 
TBA
 

Research lab


http://www.salk.edu/labs/chalasani

Audience

Free and open to the university community and the public


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Butler Seminar Series Mon, 18 Aug 2014 15:09:18 -0400
Oliver Hobert (Columbia) http://molbio.princeton.edu/events/all/event/365-hobert http://molbio.princeton.edu/events/all/event/365-hobert Location: Lewis Thomas Lab, 003 - Princeton
Category: Butler Seminar Series
Date: Wed, Feb 18, 2015 - Wed, Feb 18, 2015
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Butler Seminar Series

Speaker
Hobert-345x239 0
Oliver Hobert, Ph.D.
Columbia University Medical Center

Oliver Hobert is professor of biochemistry and molecular biophysics at Columbia University.  Dr. Hobert received his Ph.D. from Max Planck Institute for Biochemistry. The main focus of his laboratory is to understand the molecular mechanisms that generate the astounding diversity of cell types in a nervous system.

Seminar Topic

 
TBA
 

Research lab


http://hobertlab.org

Audience

Free and open to the university community and the public


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Butler Seminar Series Mon, 18 Aug 2014 15:09:18 -0400
Jody Rosenblatt (U of Utah) http://molbio.princeton.edu/events/all/event/367-rosenblatt http://molbio.princeton.edu/events/all/event/367-rosenblatt Location: Lewis Thomas Lab, 003 - Princeton
Category: Butler Seminar Series
Date: Wed, Feb 25, 2015 - Wed, Feb 25, 2015
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Butler Seminar Series

Speaker
Jody
Judy Rosenblatt, Ph.D.
University of Utah

Jody Rosenblatt is Associate Professor of Oncological Sciences at the University of Utah.  Dr. Rosenblatt received her B.A. from the University of California, Berkeley and her Ph.D. from the University of California, San Francisco.  The Rosenblatt Lab studies both cell death and cell division and the roles that the actin and microtubule cytoskeletons play in both processes. Her lab is investigating if extrusion (a contraction that squeezes dying cells out of tissue) could drive cell death in order to control cell numbers.

Seminar Topic

 
TBA
 

Research lab


http://healthcare.utah.edu/huntsmancancerinstitute/research/labs/rosenblatt/

Audience

Free and open to the university community and the public


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Butler Seminar Series Mon, 18 Aug 2014 15:09:18 -0400