Jörg Vogel (Institute of Molecular Infection Biology)
MolBio Seminar Series
Institute of Molecular Infection Biology
An RNA Perspective on Bad Microbes and Their Hosts
This talk will discuss emerging concepts of gene regulation by small noncoding RNAs in pathogenic bacteria; show how RNA deep sequencing technology has opened new avenues for the global discovery and functional study of diverse functional small RNAs in many bacterial species; introduce a new Dual RNA-seq approach which aims to take the study of host-pathogen interactions a major step further and enable us to analyse RNA expression changes in both bacterial pathogen and eukaryotic host simultaneously.
My laboratory of RNA Biology is interested in the discovery and functional characterization of small RNAs in pathogenic bacteria as well as of microRNAs and long noncoding RNAs in infected eukaryotic host cells. We use global approaches including deep sequencing, to identify regulatory RNAs and their targets, and biochemical and genetic analyses to decipher new molecular mechanisms and physiological consequences of RNA-based regulation.
Free and open to the university community and the public