Paul F. Glenn Laboratories for Aging Research at Princeton University Mini Symposium
Paul F. Glenn Laboratories for Aging Research at Princeton University
101 Carl Icahn Laboratory
1:00 – 1:20 pm Coleen T. Murphy, Director - Introduction/Welcome
1:20 – 1:40 pm Gordon Berman – "Mapping the structure of behavioral senescence in Drosophila melanogaster"
1:40 – 2:00 pm Eric Klein – "Mechanical signaling in bacterial uropathogens"
2:00 – 2:20 pm Mohammad Rahimi Lenji – "Learning and memory in C. elegans: a microfluidic assay"
Amanda Crocker – "Movement towards understanding olfactory long-term memory encoding in Drosophila melanogaster"
2:20 – 2:40 pm Kevin Takasaki – "Fluorescence light-field imaging: method and applications"
2:40 – 3:00 pm Gunnar Kleemann – "Quantitative Trait Loci analysis of longevity pathways"
Dr. Monica Driscoll
Department of Molecular Biology and Biochemistry, Rutgers University "
C. elegans secrets for healthy aging: Genes, Environment, Experience, and Luck"
Design of effective therapeutic interventions that counter the deleterious aspects of aging will require a thorough definition of what actually occurs during aging at the molecular, cellular, and systems levels, as well as targeting these processes for improved maintenance. We are using the power of the C. elegans experimental model to define genes, drugs, and experiences that extend healthspan, the period of healthy life that precedes age-associated decline. In the context of a general overview on healthspan studies, I will discuss some of our recent work on changes in dendritic regrowth, synaptic deterioration, and proteostasis in aging C. elegans neurons; on the identification of microRNAs that regulate the quality of aging, one of which acts as a switch for the dietary restriction state; and on exercise contributions to late-age maintenance.
Free and open to the university community